Epidemiological Component

The goal of the epidemiological component is to introduce G6PD testing and evaluate the feasibility of combining it with the Malakit intervention.

A strong incentive for the development of the Malakit was concern about the development of a drug-resistant P. falciparum in the region. Besides, another malaria parasite species, the Plasmodium vivax (Pv), has since become the primary cause of malaria infection in the region, indicating a clear need to associate a Pv radical treatment to the Malakit intervention.

Another concern, however, is that this treatment can badly affect individuals with a G6PD deficiency – a genetic disorder that affects the body's ability to tolerate the Pv malarial treatment. To ensure safe deployment of this approach, a test for G6PD deficiency should be included in the kit services.

Objectives

  • To build a foundation for improving Malakit's capacity to eliminate malaria in the region, including Plasmodium vivax transmission, among target populations

  • To evaluate the capacity of facilitators to carry out and interpret G6PD tests

Methodology

  • Facilitators are in charge of administering the G6PD tests. Before going to the field, they are trained to administer the tests under laboratory conditions.

  • Facilitators are also observed on the field, so that they follow the protocols they have learned during the training. Their supervisors evaluate their performance by their capability to make the right decision after obtaining the G6PD test result.